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Ambiguity Coding Allows Accurate Inference of Evolutionary Parameters from Alignments in an Aggregated State-Space

How can we best learn the history of a protein’s evolution? Ideally, a model of sequence evolution should capture both the process that generates genetic variation and the functional constraints determining which changes are fixed. However, in practical terms the most suitable approach may simply be...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Syst Biol
Päätekijät: Weber, Claudia C, Perron, Umberto, Casey, Dearbhaile, Yang, Ziheng, Goldman, Nick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744038/
https://ncbi.nlm.nih.gov/pubmed/32353118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sysbio/syaa036
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