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Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels

Common variants in the hepatic lipase (LIPC) gene have been shown to be associated with plasma lipid levels; however, the distribution and functional features of rare and regulatory LIPC variants contributing to the extreme lipid phenotypes are not well known. This study was aimed to catalogue LIPC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pirim, Dilek, Bunker, Clareann H., Hokanson, John E., Hamman, Richard F., Demirci, F. Yesim, Kamboh, M. Ilyas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743991/
https://ncbi.nlm.nih.gov/pubmed/33326441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243919
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