Profound Treg perturbations correlate with COVID-19 severity

The hallmark of severe COVID-19 disease has been an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. We explored the hypothesis that perturbations in FoxP3+ T regulatory cells (Treg), key enforcers of immune homeostasis, contribute to COVID-19 pathology...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Galvan-Pena, Silvia, Leon, Juliette, Chowdhary, Kaitavjeet, Michelson, Daniel A., Vijaykumar, Brinda, Yang, Liang, Magnuson, Angela, Manickas-Hill, Zachary, Piechocka-Trocha, Alicja, Worrall, Daniel P., Hall, Kathryn E., Ghebremichael, Musie, Walker, Bruce D., Li, Jonathan Z., Yu, Xu G., Mathis, Diane, Benoist, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743083/
https://ncbi.nlm.nih.gov/pubmed/33330871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.11.416180
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