Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients exhibit multiple organ malfunctions with a primary manifestation of acute and diffuse lung injuries. The Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to mediate viral entry into host cells; however,...

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Publicado no:bioRxiv
Main Authors: Cao, Xiaoling, Tian, Yan, Nguyen, Vi, Zhang, Yuping, Gao, Chao, Yin, Rong, Carver, Wayne, Fan, Daping, Albrecht, Helmut, Cui, Taixing, Tan, Wenbin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743069/
https://ncbi.nlm.nih.gov/pubmed/33330865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.07.414706
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