Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis

Fibroblast heterogeneity has been shown within the unwounded mouse dorsal dermis, with fibroblast subpopulations being identified according to anatomical location and embryonic lineage. Using lineage tracing, we demonstrate that paired related homeobox 1 (Prrx1)-expressing fibroblasts are responsibl...

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Udgivet i:Cell Rep
Main Authors: Leavitt, Tripp, Hu, Michael S., Borrelli, Mimi R., Januszyk, Michael, Garcia, Julia T., Ransom, Ryan C., Mascharak, Shamik, desJardins-Park, Heather E., Litzenburger, Ulrike M., Walmsley, Graham G., Marshall, Clement D., Moore, Alessandra L., Duoto, Bryan, Adem, Sandeep, Foster, Deshka S., Salhotra, Ankit, Shen, Abra H., Griffin, Michelle, Shen, Ethan Z., Barnes, Leandra A., Zielins, Elizabeth R., Maan, Zeshaan N., Wei, Yuning, Chan, Charles K.F., Wan, Derrick C., Lorenz, Hermann P., Chang, Howard Y., Gurtner, Geoffrey C., Longaker, Michael T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742512/
https://ncbi.nlm.nih.gov/pubmed/33176144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108356
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