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Design and Main Results of STURDY: A Randomized Clinical Trial of Four Vitamin D3 Doses to Prevent Falls in Older Adults

STURDY was a Bayesian, response-adaptive trial with dose-finding and confirmatory stages. Participants (n=688; ≥70years with serum 25(OH)D of 10-29ng/mL) were randomized to 200 (control), 1000, 2000, or 4000 IU/day of vitamin D3. The primary outcome was time to first fall or death over 2 years. Duri...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Appel, Lawrence, Schrack, Jennifer, Michos, Erin, Mitchell, Christine, Juraschek, Stephen, Miller, Edgar, Roth, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742404/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2737
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