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Intratumoral activation of 41BB co-stimulatory signals enhances CD8 T cell expansion and modulates tumor-infiltrating myeloid cells
The activation of 41BB co-stimulatory signals by agonistic antibodies enhances the expansion and function of tumor-infiltrating lymphocytes (TILs) for treating cancer patients with adoptive cell therapy (ACT). However, the impact of 41BB agonism is not limited to enhancing the activity of T cells an...
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| Vydáno v: | J Immunol |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7741883/ https://ncbi.nlm.nih.gov/pubmed/33020146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000759 |
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