Determining the Role of ApoE4 in Age-Related Cerebrovascular Decline

Cerebrovascular decline occurs during aging and may be critical during prodromal phases of Alzheimer’s disease (AD). The E4 allele of apolipoprotein E (APOE4) is the greatest genetic risk factor for AD and decreased longevity and studies suggest APOE4 increases risk for age-dependent cerebrovascular...

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Udgivet i:Innov Aging
Main Authors: Foley, Kate, Borchian, Peter, Garceau, Dylan, Kotredes, Kevin, Territo, Paul, Sasner, Michael, Howell, Gareth, Diemler, Cory
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741542/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.390
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