PRE-TRANSPLANT HEMOGLOBIN AND CREATININE CLEARANCE CORRELATE WITH TREATMENT FREE SURVIVAL AFTER AUTOLOGOUS STEM CELL TRANSPLANTATION FOR MULTIPLE MYELOMA

Melphalan is given at a dose of 200mg/m(2) (Mel200) prior to ASCT for multiple myeloma (MM). Pharmacokinetic (PK) studies show a high degree of interpatient variability. We aimed to test the impact of clinical factors previously shown to affect melphalan PK such as hemoglobin (Hgb), fat free mass (F...

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Udgivet i:Bone Marrow Transplant
Main Authors: Sweiss, Karen, Calip, Gregory S., Johnson, Jeremy J., Rondelli, Damiano, Patel, Pritesh R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741423/
https://ncbi.nlm.nih.gov/pubmed/31388085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41409-019-0628-8
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