Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling

Ischemic/reperfusion (I/R) injury is the primary cause of acute kidney injury (AKI). Gastrin, a gastrointestinal hormone, is involved in the regulation of kidney function of sodium excretion. However, whether gastrin has an effect on kidney I/R injury is unknown. Here we show that cholecystokinin B...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Liu, Chao, Chen, Ken, Wang, Huaixiang, Zhang, Ye, Duan, Xudong, Xue, Yuanzheng, He, Hongye, Huang, Yu, Chen, Zhi, Ren, Hongmei, Wang, Hongyong, Zeng, Chunyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740972/
https://ncbi.nlm.nih.gov/pubmed/33343341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.540479
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