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Reduction of Dendritic Inhibition in CA1 Pyramidal Neurons in Amyloidosis Models of Early Alzheimer’s Disease

BACKGROUND: In an early stage of Alzheimer’s disease (AD), before the formation of amyloid plaques, neuronal network hyperactivity has been reported in both patients and animal models. This suggests an underlying disturbance of the balance between excitation and inhibition. Several studies have high...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Ruiter, Marvin, Herstel, Lotte J., Wierenga, Corette J.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739974/
https://ncbi.nlm.nih.gov/pubmed/33074225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200527
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