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Loss of the glucocorticoid receptor causes accelerated ovarian ageing in zebrafish

Reproductive decline in mid-adult females is an established phenotype of the ageing process. Stress and the rise in glucocorticoids (GCs) accelerate reproductive ageing, but little is known about the mechanisms involved. During stress, GCs activate the glucocorticoid receptor (GR), a ubiquitously ex...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Faught, Erin, Santos, Helio B., Vijayan, Mathilakath M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739937/
https://ncbi.nlm.nih.gov/pubmed/33259761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2020.2190
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