Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice

Brain-derived neurotrophic factor (BDNF) plays essential roles in GABAergic interneuron development. The common BDNF val66met polymorphism, leads to decreased activity-dependent release of BDNF. The current study used a humanized mouse model of the BDNF val66met polymorphism to determine how reduced...

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Udgivet i:Neurobiol Stress
Main Authors: Hill, Rachel Anne, Grech, Adrienne Mary, Notaras, Michael J., Sepulveda, Mauricio, van den Buuse, Maarten
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739172/
https://ncbi.nlm.nih.gov/pubmed/33344708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100253
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