Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats

Several lines of evidence suggest that antidepressant drugs may act by modulating neuroplasticity pathways in key brain areas like the hippocampus. We have reported that chronic treatment with fasudil, a Rho-associated protein kinase inhibitor, prevents both chronic stress-induced depressive-like be...

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Détails bibliographiques
Publié dans:Neurobiol Stress
Auteurs principaux: Román-Albasini, Luciano, Díaz-Véliz, Gabriela, Olave, Felipe Antonio, Aguayo, Felipe Ignacio, García-Rojo, Gonzalo, Corrales, Wladimir Antonio, Silva, Juan Pablo, Ávalos, Ana María, Rojas, Paulina S., Aliaga, Esteban, Fiedler, Jenny Lucy
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Original Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739043/
https://ncbi.nlm.nih.gov/pubmed/33344690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100234
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