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Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity
Runt-related transcription factor 2 (RUNX2) is critical for the development of the vertebrate bony skeleton. Unlike other RUNX family members, RUNX2 possesses a variable poly-glutamine, poly-alanine (QA) repeat domain. Natural variation within this repeat is able to alter the transactivation potenti...
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| Gepubliceerd in: | Commun Biol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7738678/ https://ncbi.nlm.nih.gov/pubmed/33319865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01501-3 |
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