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Afatinib-loaded Inhalable PLGA Nanoparticles for Localized Therapy of Non-Small Cell Lung Cancer (NSCLC) – Development and In-vitro Efficacy
Afatinib (AFA) is a potent aniline-quinazoline derivative, approved by the Food and Drug Administration (FDA) in 2013, as a first-line treatment for metastatic Non-Small Cell Lung Cancer (NSCLC). However, its clinical application is highly limited by its poor solubility, and consequently low bioavai...
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| Publicado no: | Drug Deliv Transl Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7738377/ https://ncbi.nlm.nih.gov/pubmed/32557351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-020-00802-8 |
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