Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1(R206H) Mouse Model of Fibrodysplasia Ossificans Progressiva

Heterotopic ossification (HO) is a clinical condition that often reduces mobility and diminishes quality of life for affected individuals. The most severe form of progressive HO occurs in those with fibrodysplasia ossificans progressiva (FOP; OMIM #135100), a genetic disorder caused by a recurrent h...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Convente, Michael R, Chakkalakal, Salin A, Yang, EnJun, Caron, Robert J, Zhang, Deyu, Kambayashi, Taku, Kaplan, Frederick S, Shore, Eileen M
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737844/
https://ncbi.nlm.nih.gov/pubmed/28986986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3304
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