Superior Effect of the Combination of Carbon-Ion Beam Irradiation and 5-Fluorouracil on Colorectal Cancer Stem Cells in vitro and in vivo

BACKGROUND: The aim of this study was to investigate whether carbon-ion beam irradiation in combination with 5-fluorouracil (5-FU) is superior to carbon-ion beam irradiation alone in targeting colorectal cancer stem-like cells (CSCs). MATERIALS AND METHODS: Human colorectal cancer (CRC) cells, HCT11...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Koom, Woong Sub, Sai, Sei, Suzuki, Masao, Fujimori, Akira, Yamada, Shigeru, Tsujii, Hirohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737548/
https://ncbi.nlm.nih.gov/pubmed/33335403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S276035
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