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Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells

Most drugs entering clinical trials fail, often related to an incomplete understanding of the mechanisms governing drug response. Machine learning techniques hold immense promise for better drug response predictions, but most have not reached clinical practice due to their lack of interpretability a...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Kuenzi, Brent M., Park, Jisoo, Fong, Samson H., Sanchez, Kyle S., Lee, John, Kreisberg, Jason F., Ma, Jianzhu, Ideker, Trey
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737474/
https://ncbi.nlm.nih.gov/pubmed/33096023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.09.014
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