Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model

BACKGROUND: Previous studies noted that intravitreal injection of S100B triggered a glaucoma-like degeneration of retina and optic nerve as well as microglia activation after 14 days. The precise role of microglia in our intravitreal S100B model is still unclear. Hence, microglia were inhibited thro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Grotegut, Pia, Perumal, Natarajan, Kuehn, Sandra, Smit, Andreas, Dick, H. Burkhard, Grus, Franz H., Joachim, Stephanie C.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737388/
https://ncbi.nlm.nih.gov/pubmed/33317557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02012-y
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