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Elucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses

Transcriptional regulators are prevalent among identified prions in Saccharomyces cerevisiae, however, it is unclear how prions affect genome-wide transcription. We show here that the prion ([SWI(+)]) and mutant (swi1∆) forms of Swi1, a subunit of the SWI/SNF chromatin-remodeling complex, confer dra...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Du, Zhiqiang, Regan, Jeniece, Bartom, Elizabeth, Wu, Wei-Sheng, Zhang, Li, Goncharoff, Dustin Kenneth, Li, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736884/
https://ncbi.nlm.nih.gov/pubmed/33318504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77993-0
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