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Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells (hMSCs) and the role it may play in hMSC-mediated...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dorronsoro, Akaitz, Lang, Valérie, Ferrin, Izaskun, Fernández-Rueda, Jon, Zabaleta, Lorea, Pérez-Ruiz, Estibaliz, Sepúlveda, Pilar, Trigueros, César
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736882/
https://ncbi.nlm.nih.gov/pubmed/33318571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78864-4
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