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MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells

MZB1 is an endoplasmic reticulum (ER)-resident protein that plays an important role in the humoral immune response by enhancing the interaction of the μ immunoglobulin (Ig) heavy chain with the chaperone GRP94 and by augmenting the secretion of IgM. Here, we show that MZB1 is also expressed in plasm...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Kapoor, Tanya, Corrado, Mauro, Pearce, Erika L., Pearce, Edward J., Grosschedl, Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736851/
https://ncbi.nlm.nih.gov/pubmed/33318509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78293-3
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