Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma

Protein homeostasis is critical for maintaining eukaryotic cell function as well as responses to intrinsic and extrinsic stress. The proteasome is a major portion of the proteolytic machinery in mammalian cells and plays an important role in protein homeostasis. Multiple myeloma (MM) is a plasma cel...

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Xehetasun bibliografikoak
Argitaratua izan da:Blood Cancer J
Egile Nagusiak: Gu, Yanyan, Barwick, Benjamin G., Shanmugam, Mala, Hofmeister, Craig C., Kaufman, Jonathan, Nooka, Ajay, Gupta, Vikas, Dhodapkar, Madhav, Boise, Lawrence H., Lonial, Sagar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736847/
https://ncbi.nlm.nih.gov/pubmed/33318477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00393-0
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