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High resolution biosensor to test the capping level and integrity of mRNAs
5′ Cap structures are ubiquitous on eukaryotic mRNAs, essential for post-transcriptional processing, translation initiation and stability. Here we describe a biosensor designed to detect the presence of cap structures on mRNAs that is also sensitive to mRNA degradation, so uncapped or degraded mRNAs...
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| Опубликовано в: : | Nucleic Acids Res |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736790/ https://ncbi.nlm.nih.gov/pubmed/33152073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa955 |
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