Aging reduces the sensitivity to the reinforcing efficacy of morphine

The US geriatric population is growing and using more opioids than ever before. The purpose of this study was to determine whether aging influenced the reinforcing efficacy of morphine in male and female rats using a rodent intravenous self-administration paradigm. Male and female aged (20–24 months...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Bongiovanni, Angela R., Peer, Kyle, Carpenter, Rachel E., Ellis, Alexandra S., Duggan, Michael R., Parikh, Vinay, Wimmer, Mathieu E.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736565/
https://ncbi.nlm.nih.gov/pubmed/33120086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.09.020
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