Dexamethasone Prodrug Nanomedicine (ZSJ-0228) Treatment Significantly Reduces Lupus Nephritis in Mice without Measurable Side Effects – A 5-Month Study

Lupus nephritis (LN) is a major cause of morbidity and mortality among systemic lupus erythematosus patients. Glucocorticoids (GC) are uniformly used in clinical LN management. Their notorious toxicities, however, have hampered the long-term clinical application. To circumvent GC side effects while...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Zhao, Zhifeng, Jia, Zhenshan, Foster, Kirk W., Wei, Xin, Qiao, Fangfang, Jiang, Haochen, Jin, Yan, Li, Guojuan, Chen, Ningrong, Zhao, Gang, Thiele, Geoffrey M., Medlin, Jennifer L., O’Dell, James R., Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736168/
https://ncbi.nlm.nih.gov/pubmed/32980548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2020.102302
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