HLA-DP mismatch and CMV reactivation increase risk of aGVHD independently in recipients of allogeneic stem cell transplant

HLA-DP mismatched allogeneic hematopoietic stem cell transplantation (allo-HCT) is associated with increased risk of aGVHD and decreased risk of relapse with no effects on overall survival (OS). It has been proposed that CMV-reactivation induces expression of HLA-DP molecules on GVHD target tissues...

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Publicado no:Curr Res Transl Med
Main Authors: Ghobadi, Armin, Milton, Denái R., Gowda, Lohith, Rondon, Gabriela, Chemaly, Roy F, Hamdi, Amir, Alousi, Amin, Afrough, Aimaz, Oran, Betul, Ciurea, Stefan, Kebriaei, Partow, Popat, Uday R., Qazilbash, Muzaffar H., Shpall, Elizabeth J., Champlin, Richard E., Bashir, Qaiser
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735254/
https://ncbi.nlm.nih.gov/pubmed/30683577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.retram.2019.01.001
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