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C3 Glomerulopathy-associated with a Monoclonal Ig is a distinct subtype

Monoclonal immunoglobulins (MIg) may play a causal role in C3G by impairing regulation of the alternative pathway of complement. Ninety-five C3G patients were tested for MIg of which 36 (37.9%) were positive. Mean age at diagnosis was 60 years; among patient’s ≥50 years 65.1% had a MIg. At presentat...

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Publicat a:Kidney Int
Autors principals: Ravindran, Aishwarya, Fervenza, Fernando C., Smith, Richard JH, Sethi, Sanjeev
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735221/
https://ncbi.nlm.nih.gov/pubmed/29729982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.01.037
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