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Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors

Chemoresistance to gemcitabine (GEM) - a frontline chemotherapeutic, resulting from its dysfunctional uptake and metabolism in cancer cells, is a major contributing factor for failed therapy in pancreatic cancer (PanC) patients. Therefore, there is an urgent need for agents that could reverse GEM re...

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Vydáno v:Mol Carcinog
Hlavní autoři: Dhar, Deepanshi, Raina, Komal, Kumar, Dileep, Wempe, Michael F., Bagby, Stacey M, Pitts, Todd M, Orlicky, David J., Agarwal, Chapla, Messersmith, Wells A, Agarwal, Rajesh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735206/
https://ncbi.nlm.nih.gov/pubmed/32816368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23251
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