Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration

Glucocorticoids are considered first-line therapy in a variety of eosinophilic disorders. They lead to a transient, profound decrease in circulating human eosinophils within hours of administration. The phenomenon of glucocorticoid-induced eosinopenia has been the basis for the use of glucocorticoid...

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Veröffentlicht in:Blood
Hauptverfasser: Hong, So Gun, Sato, Noriko, Legrand, Fanny, Gadkari, Manasi, Makiya, Michelle, Stokes, Kindra, Howe, Katherine N., Yu, Shiqin Judy, Linde, Nathaniel Seth, Clevenger, Randall R., Hunt, Timothy, Hu, Zonghui, Choyke, Peter L., Dunbar, Cynthia E., Klion, Amy D., Franco, Luis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735160/
https://ncbi.nlm.nih.gov/pubmed/32659786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005161
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