Loss of exosomal miR-146a-5p from cancer-associated fibroblasts after androgen deprivation therapy contributes to prostate cancer metastasis

BACKGROUND: Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will inevitably occur. Cancer-associated fibroblasts (CAFs) may be implicated in promoting metastasis of P...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhang, Yu, Zhao, Jing, Ding, Mao, Su, Yiming, Cui, Di, Jiang, Chenyi, Zhao, Sheng, Jia, Gaozhen, Wang, Xiaohai, Ruan, Yuan, Jing, Yifeng, Xia, Shujie, Han, Bangmin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734763/
https://ncbi.nlm.nih.gov/pubmed/33317606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01761-1
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