Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice

BACKGROUND: Immune molecules, such as cytokines, complement, and major histocompatibility complex (MHC) proteins, in the central nervous system are often associated with neuropsychiatric disorders. Neuronal MHC class I (MHCI), such as H-2D, regulate neurite outgrowth, the establishment and function...

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Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Wulaer, Bolati, Hada, Kazuhiro, Sobue, Akira, Itoh, Norimichi, Nabeshima, Toshitaka, Nagai, Taku, Yamada, Kiyofumi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734728/
https://ncbi.nlm.nih.gov/pubmed/33317605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00710-5
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