Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

The availability of an autologous transplantable auxiliary liver would dramatically affect the treatment of liver disease. Assembly and function in vivo of a bioengineered human liver derived from induced pluripotent stem cells (iPSCs) has not been previously described. By improving methods for live...

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Vydáno v:Cell Rep
Hlavní autoři: Takeishi, Kazuki, de l’Hortet, Alexandra Collin, Wang, Yang, Handa, Kan, Guzman-Lepe, Jorge, Matsubara, Kentaro, Morita, Kazutoyo, Jang, Sae, Haep, Nils, Florentino, Rodrigo M., Yuan, Fangchao, Fukumitsu, Ken, Tobita, Kimimasa, Sun, Wendell, Franks, Jonathan, Delgado, Evan R., Shapiro, Erik M., Fraunhoffer, Nicolas A., Duncan, Andrew W., Yagi, Hiroshi, Mashimo, Tomoji, Fox, Ira J., Soto-Gutierrez, Alejandro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734598/
https://ncbi.nlm.nih.gov/pubmed/32492423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107711
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