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Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib

In this study, we aimed at the application of the concept of photopharmacology to the approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib. In a previous study, we found out that the photoisomerization of axitinib’s stilbene-like double bond is unidirectional in a...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Heintze, Linda, Schmidt, Dorian, Rodat, Theo, Witt, Lydia, Ewert, Julia, Kriegs, Malte, Herges, Rainer, Peifer, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734574/
https://ncbi.nlm.nih.gov/pubmed/33255816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238961
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