Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor

Follicle-stimulating hormone receptor (FSHR) is a G protein-coupled receptor (GPCR) with pivotal roles in reproduction. One key mechanism dictating the signal activity of GPCRs is membrane trafficking. After binding its hormone FSH, FSHR undergoes internalization to very early endosomes (VEEs) for i...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Pharmacol
Hlavní autoři: Sposini, Silvia, De Pascali, Francesco, Richardson, Rachel, Sayers, Niamh S., Perrais, David, Yu, Henry N., Palmer, Stephen, Nataraja, Selva, Reiter, Eric, Hanyaloglu, Aylin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734412/
https://ncbi.nlm.nih.gov/pubmed/33329002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.593492
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky