Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases

Ectonucleoside triphosphate diphosphohydrolases (NTPDases) are ectoenzymes that play an important role in the hydrolysis of nucleoside triphosphate and diphosphate to nucleoside monophosphate. NTPDase1, -2, -3 and -8 are the membrane bound members of this enzyme family that are responsible for regul...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Afzal, Saira, al-Rashida, Mariya, Hameed, Abdul, Pelletier, Julie, Sévigny, Jean, Iqbal, Jamshed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734281/
https://ncbi.nlm.nih.gov/pubmed/33328992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.585876
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