Collective cancer cell invasion in contact with fibroblasts through integrin‐α5β1/fibronectin interaction in collagen matrix

Interaction of cancer cells with cancer‐associated fibroblasts (CAFs) plays critical roles in tumor progression. Recently we proposed a new tumor invasion mechanism in which invasive cancer cells individually migrate on elongate protrusions of CAFs (CAF fibers) in 3‐D collagen matrix. In this mechan...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Miyazaki, Kaoru, Togo, Shinsaku, Okamoto, Reiko, Idiris, Alimjan, Kumagai, Hiromichi, Miyagi, Yohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734169/
https://ncbi.nlm.nih.gov/pubmed/32979884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14664
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