Lectin drug conjugate therapy for colorectal cancer

Drug resistance represents an obstacle in colorectal cancer (CRC) treatment because of its association with poor prognosis. rBC2LCN is a lectin isolated from Burkholderia that binds cell surface glycans that have fucose moieties. Because fucosylation is enhanced in many types of cancers, this lectin...

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Vydáno v:Cancer Sci
Hlavní autoři: Kitaguchi, Daichi, Oda, Tatsuya, Enomoto, Tsuyoshi, Ohara, Yusuke, Owada, Yohei, Akashi, Yoshimasa, Furuta, Tomoaki, Yu, Yang, Kimura, Sota, Kuroda, Yukihito, Kurimori, Ko, Miyazaki, Yoshihiro, Furuya, Kinji, Shimomura, Osamu, Tateno, Hiroaki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734164/
https://ncbi.nlm.nih.gov/pubmed/33058342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14687
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