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Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils

Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibitors of innate host defense. However, there are few data tha...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Jinno, Akiko, Hayashida, Atsuko, Jenkinson, Howard F., Park, Pyong Woo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733941/
https://ncbi.nlm.nih.gov/pubmed/33293379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01907-20
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