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Identification of CD8(+) T cell epitopes through proteasome cleavage site predictions

BACKGROUND: We previously introduced PCPS (Proteasome Cleavage Prediction Server), a web-based tool to predict proteasome cleavage sites using n-grams. Here, we evaluated the ability of PCPS immunoproteasome cleavage model to discriminate CD8(+) T cell epitopes. RESULTS: We first assembled an epitop...

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Publicat a:BMC Bioinformatics
Autors principals: Gomez-Perosanz, Marta, Ras-Carmona, Alvaro, Lafuente, Esther M., Reche, Pedro A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733697/
https://ncbi.nlm.nih.gov/pubmed/33308150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03782-1
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