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Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a 5-year survival rate of <8%. Unsupervised clustering of 76 PDAC patients based on intron retention (IR) events resulted in two clusters of tumors (IR-1 and IR-2). While gene expression-based clusters are not predictive of pati...
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| Publié dans: | NPJ Genom Med |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733475/ https://ncbi.nlm.nih.gov/pubmed/33311498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-020-00159-4 |
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