Adaptive randomised controlled non-inferiority multicentre trial (the Ketodex Trial) on intranasal dexmedetomidine plus ketamine for procedural sedation in children: study protocol

INTRODUCTION: Up to 40% of orthopaedic injuries in children require a closed reduction, almost always necessitating procedural sedation. Intravenous ketamine is the most commonly used sedative agent. However, intravenous insertion is painful and can be technically difficult in children. We hypothesi...

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Pubblicato in:BMJ Open
Autori principali: Poonai, Naveen, Coriolano, Kamary, Klassen, Terry, Heath, Anna, Yaskina, Maryna, Beer, Darcy, Sawyer, Scott, Bhatt, Maala, Kam, April, Doan, Quynh, Sabhaney, Vikram, Offringa, Martin, Pechlivanoglou, Petros, Hickes, Serena, Ali, Samina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Paediatrics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733175/
https://ncbi.nlm.nih.gov/pubmed/33303457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-041319
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