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Neohesperidin Ameliorates Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting the Histone Modification of lncRNA HOTAIR

BACKGROUND: Neohesperidin (NH) and lncRNA HOTAIR (HOTAIR) could regulate osteoclastic and osteogenic differentiation. This study aimed to explore whether HOTAIR-mediated osteogenic differentiation was regulated by NH. METHODS: Steroid-induced osteonecrosis of the femoral head (SONFH) mice model was...

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Publicado en:Drug Des Devel Ther
Autores principales: Yuan, Shuai, Zhang, Chuanxin, Zhu, Yunli, Wang, Bo
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733036/
https://ncbi.nlm.nih.gov/pubmed/33324039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S255276
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