Inclusion of non-inferiority analysis in superiority-based clinical trials with single-arm, two-stage Simon's design

INTRODUCTION: Non-inferiority (NI) analysis is not usually considered in the early phases of clinical development. In some negative phase II trials, a post-hoc NI analysis justified additional phase III trials that were successful. However, the risk of false positive achievements was not controlled...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: Sampayo-Cordero, Miguel, Miguel-Huguet, Bernat, Pérez-García, José, Páez, David, Guerrero-Zotano, Ángel L., Garde-Noguera, Javier, Aguirre, Elena, Holgado, Esther, López-Miranda, Elena, Huang, Xin, Malfettone, Andrea, Llombart-Cussac, Antonio, Cortés, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733004/
https://ncbi.nlm.nih.gov/pubmed/33336109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2020.100678
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados