Receptor-targeted engineered probiotics mitigate lethal Listeria infection

Probiotic bacteria reduce the intestinal colonization of pathogens. Yet, their use in preventing fatal infection caused by foodborne Listeria monocytogenes (Lm), is inconsistent. Here, we bioengineered Lactobacillus probiotics (BLP) to express the Listeria adhesion protein (LAP) from a non-pathogeni...

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Vydáno v:Nat Commun
Hlavní autoři: Drolia, Rishi, Amalaradjou, Mary Anne Roshni, Ryan, Valerie, Tenguria, Shivendra, Liu, Dongqi, Bai, Xingjian, Xu, Luping, Singh, Atul K., Cox, Abigail D., Bernal-Crespo, Victor, Schaber, James A., Applegate, Bruce M., Vemulapalli, Ramesh, Bhunia, Arun K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732855/
https://ncbi.nlm.nih.gov/pubmed/33311493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20200-5
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