Aspirin and 5-Aminoimidazole-4-carboxamide Riboside Attenuate Bovine Ephemeral Fever Virus Replication by Inhibiting BEFV-Induced Autophagy

Recent study in our laboratory has demonstrated that BEFV-induced autophagy via activation of the PI3K/Akt/NF-κB and Src/JNK pathways and suppression of the PI3K-AKt-mTORC1 pathway is beneficial for virus replication. In the current study, we found that both aspirin and 5-aminoimidazole-4-carboxamid...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tseng, Hsu-Hung, Huang, Wei-Ru, Cheng, Ching-Yuan, Chiu, Hung-Chuan, Liao, Tsai-Ling, Nielsen, Brent L., Liu, Hung-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732683/
https://ncbi.nlm.nih.gov/pubmed/33329515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.556838
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