Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation

The contribution of dysregulated mitochondrial gene expression and consequent imbalance in biogenesis is not well understood in metabolic disorders such as insulin resistance and obesity. The ribosomal RNA maturation protein PTCD1 is essential for mitochondrial protein synthesis and its reduction ca...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Perks, Kara L., Ferreira, Nicola, Ermer, Judith A., Rudler, Danielle L., Richman, Tara R., Rossetti, Giulia, Matthews, Vance B., Ward, Natalie C., Rackham, Oliver, Filipovska, Aleksandra
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732297/
https://ncbi.nlm.nih.gov/pubmed/33024056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104010
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