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Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease

RNA modifications modulate most steps of gene expression. However, little is known about its role in neuroblastoma (NBL) and the inhibitors targeting it. We analyzed the RNA-seq (n=122) and CNV data (n=78) from NBL patients in Therapeutically Applicable Research to Generate Effective Treatments (TAR...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ma, Pei, Yue, Lifeng, Zhang, Sen, Hao, Dacheng, Wu, Zhihong, Xu, Lijia, Du, Guanhua, Xiao, Peigen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732279/
https://ncbi.nlm.nih.gov/pubmed/33044945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103671
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