Size-transformable antigen-presenting cell–mimicking nanovesicles potentiate effective cancer immunotherapy

Artificial antigen-presenting cells (aAPCs) can stimulate CD8(+) T cell activation. While nanosized aAPCs (naAPCs) have a better safety profile than microsized (maAPCs), they generally induce a weaker T cell response. Treatment with aAPCs alone is insufficient due to the lack of autologous antigen-s...

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Vydáno v:Sci Adv
Hlavní autoři: Yang, Weijing, Deng, Hongzhang, Zhu, Shoujun, Lau, Joseph, Tian, Rui, Wang, Sheng, Zhou, Zijian, Yu, Guocan, Rao, Lang, He, Liangcan, Ma, Ying, Chen, Xiaoyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732193/
https://ncbi.nlm.nih.gov/pubmed/33310853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd1631
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